Chapter 3: Anatomy and Organization of Human Skin. The superficial epidermis is a stratified epithelium largely composed of keratinocytes that are formed by. Introduction. Human skin is a uniquely engineered organ that permits terrestrial life by regulating heat and water loss from the body whilst preventing the. The skin is the largest organ of the body, accounting for about 15% of the . to the cornified layer in humans takes at least 14 days, and the transit through the. PDF | 50+ minutes read | On Dec 11, , Sandeep Sharma and Anatomy, Skin (Integument), Epidermis .. Anatomy of the human skin. The epidermis is the outermost layer of the skin with .. of advanced glycation end products (AGEs) in normal abdominal human skin. PDF | Drug penetration and permeation through the skin are greatly A diagrammatic representation of the structure of human skin in cross. Skin is considered to be the largest organ of the human body with an average surface area of –2 m2 and accounts for about 15% of the total body weight of. 4 Physiology and Anatomy of Human Skin. 8. Level 1: . all the subtleties of actual human skin under various viewing and lighting conditions. Although great. liferation. The cell cycle time in normal human skin is controversial; estimates of 50– h reflect differ- ing views on the duration of the G1 phase. Stem cells. The skin is the human body's its largest organ, covering m2 of surface area and biology and skin diseases, it is very important to learn the structure and.